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Eag and HERG potassium channels as novel therapeutic targets in cancer.
(2010-12)Voltage gated potassium channels have been extensively studied in relation to cancer. In this review, we will focus on the role of two potassium channels, Ether à-go-go (Eag), Human ether à-go-go related gene (HERG), in ... -
Eagle's syndrome: The anatomical basis
(2015-04)Eagle's syndrome, also known as styloid artery syndrome, is a symptom complex associated with elongation of the temporal styloid process or calcification of the stylohyoid ligament. There is high anatomical variability in ... -
Early Class II treatment
(2017)The treatment of children presenting with a Class II division I malocclusion involves one of two approaches. The first provides treatment in two phases; one of intervention during the mixed dentition (phase I) followed by ... -
Early management of sepsis
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The Early Memories of Warmth and Safeness Scale for adolescents: Cross-Sample Validation of the Complete and Brief Versions
(2017)This work presents psychometric analyses on the Early Memories of Warmth and Safeness Scale, which intends to evaluate the subjective perception of ones' early rearing experiences. Factor structure, measurement invariance, ... -
Early onset type 2 diabetes: risk factors, clinical impact and management.
(2014-11)Early onset type 2 diabetes mellitus (T2DM) is increasingly prevalent with a significant impact on the individual, healthcare service delivery and planning. The individuals are likely to be obese, lead a sedentary lifestyle, ... -
Early prognostic factors in distal radius fractures in a younger than osteoporotic age group: a multivariate analysis of trauma radiographs.
(2013-05)BACKGROUND: Treatment of distal radius fractures in patients of a younger than osteoporotic age is complex, because they often are the result of a high-energy trauma and have intra-articular fractures and associated injuries. ... -
Early results after vertebral body stenting for fractures of the anterior column of the thoracolumbar spine.
(2011-10)INTRODUCTION: Vertebroplasty and balloon kyphoplasty have shown to improve pain and functional outcome in cases with symptomatic vertebral fractures. Although restoration of the vertebral body height and kyphosis seemed ... -
Eccentric exercise increases circulating fibroblast activation protein but not bioactive fibroblast growth factor 21 in healthy humans.
(2018-04)NEW FINDINGS: What is the central question of this study? The role of FGF21 as an exercise-induced myokine remains controversial. The aim of this study was to determine whether eccentric exercise would augment the release ... -
Education and Training Needs in Radiation Oncology in India: Opportunities for Indo-US Collaborations.
(2015-12)Purpose: To conduct a survey of radiation oncologists in India, to better understand specific educational needs of radiation oncology in India and define areas of collaboration with US institutions. Methods and Materials: ... -
Effect of agomelatine 25-50mg on functional outcomes in patients with major depressive disorder
(2018)Purpose: The purpose of this work is to investigate the effect of agomelatine on functioning compared with placebo in patients suffering from Major Depressive Disorder (MDD). Methods: Data from two randomized, parallel, ... -
Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells
(2017)Background: Antipsychotics (APs) are widely prescribed drugs, which are well known to cause reproductive adverse effects through mechanisms yet to be determined. The purpose of this study was to investigate the effect of ... -
Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study.
(2013-03)BACKGROUND: Colon cancer (CC) patients commonly suffer declines in muscle mass and aerobic function. We hypothesised that CC would be associated with reduced muscle mass and mitochondrial enzyme activity and that curative ... -
The effect of conventional versus figure-of-eight module ligation on mandibular incisor alignment: a randomised controlled trial.
(2017-12)OBJECTIVETo determine whether using figure-of-eight modules affects the rate of lower incisor alignment compared with conventionally tied modules.DESIGNProspective randomised controlled trial.SETTINGOrthodontic department ... -
Effect of diabetes on the cutaneous microcirculation of the feet in patients with intermittent claudication.
(2015-10)AIMS: To evaluate endothelial-dependent and - independent cutaneous vasodilator responses in the feet of patients with peripheral arterial disease (PAD) with or without Type 2 diabetes. METHODS: Cutaneous microvascular ... -
Effect of ethnicity on live birth rates after in vitro fertilisation/intracytoplasmic sperm injection treatment: analysis of UK national database.
(2016-08)OBJECTIVE: To evaluate the effect of ethnicity of women on the outcome of in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) treatment. DESIGN: Observational cohort study. SETTING: UK National Database. ... -
Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial.
(2015-07)BACKGROUND: Maternal obesity is associated with increased birthweight, and obesity and premature mortality in adult offspring. The mechanism by which maternal obesity leads to these outcomes is not well understood, but ... -
Effect of noise on tasks in operating theatres: a survey of the perceptions of healthcare staff
(2017)Noise in the operating theatre has an adverse impact on healthcare professionals, both physically and psychologically. It can be distracting, make communication difficult, and contribute to a perceived increase in stress. ... -
Effect of preoperative two-dimensional animation information on perioperative anxiety and knowledge retention in patients undergoing bowel surgery: a randomized pilot study.
(2013-05)AIM: The use of multimedia information provided preoperatively can potentially reduce anxiety in patients and improve the hospital experience. However, the use of two-dimensional (2D) animation (cartoon) to provide ... -
Effect of second timed appointments for non-attenders of breast cancer screening in England: a randomised controlled trial.
(2017-05)BACKGROUND: In England, participation in breast cancer screening has been decreasing in the past 10 years, approaching the national minimum standard of 70%. Interventions aimed at improving participation need to be ...
