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Now showing items 885-904 of 1723
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Lamotrigine for people with borderline personality disorder: A Randomised Control Trial
(2018)Background: No drug treatments are currently licensed for the treatment of borderline personality disorder (BPD). Despite this, people with this condition are frequently prescribed psychotropic medications and often with ... -
Language matters. Addressing the use of language in the care of people with diabetes: position statement of the English Advisory Group.
(2018-06)The language used by healthcare professionals can have a profound impact on how people living with diabetes, and those who care for them, experience their condition and feel about living with it day-to-day. At its best, ... -
Laparoscopic Roux en-Y Gastric Bypass Using a Modified Retrocolic-Supracolic Approach: Outcomes from 300 Patients.
(2016-03)BACKGROUND: Laparoscopic Roux en-Y gastric bypass (LRYGB) achieves sustained long-term weight loss and reduced mortality in morbidly obese patients. It is routinely performed using an ante- or retrocolic approach with the ... -
Laryngeal sensory testing in the assessment of patients with laryngopharyngeal reflux.
(2012-03)Laryngopharyngeal reflux is commonly encountered in the ENT out-patient setting. It leads to impaired sensory capacity of the laryngeal mucosa. The sensory integrity of the laryngopharynx can be evaluated through endoscopic ... -
Late discovery of a case with TAR syndrome who presented with an additional potential bleeding risk other than thrombocytopenia
(2013-04)The name of this syndrome based on an acronym describing the so called 'most obvious' clinical features: Absent Radii & Thrombocytopenia (TAR). There may however be more to TAR cases than what the name says. Development ... -
Learning about research: How can trainees in rehabilitation medicine become competent in appraising and conducting research?
(2010-12)This series of articles for rehabilitation in practice aims to cover a knowledge element of the rehabilitation medicine curriculum. Nevertheless they are intended to be of interest to a multidisciplinary audience. The ... -
Learning disability: experience of diagnosis
(2014)Studies have focused on the experience of diagnosis from the perspectives of parents of children with learning disabilities, but there has been limited methodologically rigorous investigation into the experience for the ... -
Legacy of COVID-19 - the opportunity to enhance surgical services for patients with colorectal disease.
(2020-08)After wide consultation with trainees, trainers, employers and other stakeholders, the new General Surgical Curriculum was approved earlier this year and will be implemented from 4 August 2021. It will be outcome based and ... -
Legg-Calvé-Perthes: interobserver and intraobserver reliability of the modified Herring lateral pillar classification.
(2013-03)The purpose of our study was to independently assess the reliability of the modified Herring lateral pillar classification. METHODS: Thirty-five standardized true anteroposterior radiographs of children in the fragmentation ... -
Lenalidomide before and after ASCT for transplant-eligible patients of all ages in the randomized, phase III, Myeloma XI trial.
(2020-06)The optimal way to use immunomodulatory drugs as components of induction and maintenance therapy for multiple myeloma is unresolved. We addressed this question in a large phase III randomized trial, Myeloma XI. Patients ... -
Leptin as a neuroprotective agent in glaucoma.
(2013-11)Glaucoma is a disease characterized by progressive optic nerve degeneration and is the leading cause of irreversible blindness worldwide. More than 60 million people globally are affected by glaucoma, of which 8 million ... -
Less is more: re-evaluating systematic reviews.
(2018-08) -
Lesson of the month 1: Prolonged QT syndrome due to donepezil: a reversible cause of falls?
(2019)Prolonged QT syndrome precipitates cardiac arrhythmias such as torsades de pointes (TdP) resulting in cardiogenic syncope or sudden death. We report a case of prolonged QT syndrome caused by donepezil which resulted in a ... -
Lethal End of Spectrum of Clots-Thrombotic Storm.
(2018-05-27)Thrombotic storm (TS) is a rare, acute, hypercoagulable state characterized by multiple thromboembolic events affecting at least two different areas of the vascular system/organs over a short period of time. Typical triggers ... -
LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial.
(2018-09)BACKGROUND: The LeucoPatch device uses bedside centrifugation without additional reagents to generate a disc comprising autologous leucocytes, platelets, and fibrin, which is applied to the surface of the wound. We aimed ... -
Lidocaine-prilocaine cream versus local infiltration anaesthesia in pain relief during repair of perineal trauma after vaginal delivery: a systematic review and meta-analysis.
(2018-08)BACKGROUND: Perineal trauma is a common problem that may affect women during vaginal delivery; this trauma can either spontaneous (tear) or intentional (episiotomy). When repair of perineal trauma is required, adequate ... -
Lifelong learning in obstetrics and gynaecology: how theory can influence clinical practice
(2011)Lifelong learning refers to the systematic acquisition, renewal, updating and completion of knowledge. It is synonymous with the term 'self-directed learning'. This is a new educational strategy meant to consolidate knowledge ... -
Limited capsular release and controlled manipulation under anaesthesia for the treatment of frozen shoulder.
(2016-01)Background In light of recent interest in the cost-effectiveness of the treatment options available for frozen shoulder, we aimed to determine the results of limited anterior capsular release and controlled manipulation ... -
LIMPRINT in Specialist Lymphedema Services in United Kingdom, France, Italy, and Turkey.
(2019-04)Background: There is no standardized international model for specialist lymphedema services, which covers the types of lymphedema treated and the treatments provided. The aim of this study was to provide a profile of ...
