Browsing by Title
Now showing items 1254-1273 of 1615
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Safe investigation of isolated change in bowel habit with a flexible sigmoidoscopy? A systematic review and meta-analysis.
(2019-07)INTRODUCTION: Public awareness campaigns have led to increasing referrals of patients to colorectal surgery for possible cancer. Change in bowel habit, is traditionally described as a symptom of a left sided bowel cancer. ... -
Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial.
(2017-01)BACKGROUND: Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess ... -
Safety and feasibility of breast lesion localization using magnetic seeds (Magseed): a multi-centre, open-label cohort study.
(2018-02)PURPOSE: Wire localization has several disadvantages, notably wire migration and difficulty scheduling the procedure close to surgery. Radioactive seed localization overcomes these disadvantages, but implementation is ... -
Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study.
(2017-01)Background: Significant safety concerns remain surrounding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) following gastrointestinal surgery, leading to wide variation in their use. This study aimed to determine ... -
Safety of short, in-hospital delays before surgery for acute appendicitis: Multicentre cohort study, systematic review, and meta-analysis
(2014-05)To determine safety of short in-hospital delays before appendicectomy. BACKGROUND: Short organizational delays before appendicectomy may safely improve provision of acute surgical services. METHODS: The primary endpoint ... -
Same day arterial embolisation followed by hepatic resection for treatment of giant haemangioma.
(2016-02)Cavernous haemangiomas are the most common tumour of the liver; they are benign in nature and have an incidence of up to 7.3% at autopsy. Occasionally, they may cause symptoms necessitating intervention. We report the case ... -
Scapholunate interosseus ligament reconstruction on a cadaver: A technique
(2014-09)BACKGROUND: Acute rupture of the scapholunate interosseus ligament is a relatively frequent occurrence which can be repaired primarily by direct suturing. However, patients are often seen a few weeks after injury when most ... -
Scarf osteotomy in the management of symptomatic adolescent hallux valgus.
(2012-06)PURPOSE: This study was designed to assess the utility of the scarf osteotomy in the management of symptomatic adolescent hallux valgus. MATERIALS AND METHODS: This is a case series of 29 patients (39 feet) with a mean ... -
School-entry vision screening in the United Kingdom: practical aspects and outcomes
(2014)PURPOSE: To describe and assess an orthoptist-led vision screening service for school-entry (reception class) children, and report outcomes from one healthcare trust in the UK. METHODS: A total of 3721 children (aged 4-5 ... -
Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease
(2016)Early-onset Alzheimer's disease (EOAD) can be familial (FAD) or sporadic EOAD (sEOAD); both have a disease onset <65 years of age. A total of 451 sEOAD samples were screened for known causative mutations in exons 16 and ... -
Screening for dementia in primary care.
(2013)The literature on the diagnosis of dementia in primary care has been summarised in a meta-analysis that indicated that GPs recognise three in four patients with dementia using clinical judgment alone whilst highlighting ... -
Screening of the cervical spine in subacromial shoulder pain: A systematic review
(2018-07)Background: Subacromial shoulder pain is a common clinical presentation with much diagnostic uncertainty. Some of this uncertainty relates to the involvement of the cervical spine as a source or contribution to subacromial ... -
Seeking beauty: understanding the psychology behind orthognathic surgery.
(2015-12)Orthognathic surgery to correct serious skeletal discrepancies of the jaw improves both function and appearance, but patients should spend a lot of time thinking about, discussing, and planning operations that have such a ... -
Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro.
(2018-02)BACKGROUND: Oestrogen receptors (ER) have a well-established role to the initiation, progression and regulation of responses to treatment of breast, prostate, and lung cancers. Previous data indicates altered ER expression ... -
Self-harm and life problems: findings from the Multicentre Study of Self-harm in England.
(2016)Self-harm is a major clinical problem and is strongly linked to suicide. It is important to understand the problems faced by those who self-harm to design effective clinical services and suicide prevention strategies. We ... -
Self-harm is common in adolescents in England
(2013)Question: What are the epidemiology and characteristics of self-harm in adolescents in England? Population: In total, 5205 children and adolescents aged up to 18 presenting with self-harm to general hospital emergency ...
