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Now showing items 1003-1022 of 1801
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Medium-Long-Term Clinical and Radiographic Outcomes of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) for Central Primary Metatarsalgia: Do Maestro Criteria Have a Predictive Value in the Preoperative Planning for This Percutaneous Technique?
(2018-11)Background: The purpose of this prospective study was first to evaluate the safety and effectiveness of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) in treating central metatarsalgia, identifying ... -
Medium-term clinical results of a linked total elbow replacement system.
(2014-10)Medium-term results of the Discovery elbow replacement are presented. We reviewed 51 consecutive primary Discovery total elbow replacements (TERs) implanted in 48 patients. The mean age of the patients was 69.2 years (49 ... -
Menopause and the NHS: caring for and retaining the older workforce
(2019-09)Menopause is a natural transition affecting most women between the ages of 45 and 55. Three-quarters of women will experience mild to moderate menopausal symptoms and a further quarter will report them as severe. Symptoms ... -
Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer.
(2019-11)The major changes in hormone levels that occur through the menstrual cycle have been postulated to affect the expression of hormone-regulated and proliferation-associated genes (PAGs) in premenopausal ER+ breast cancer. ... -
Mesalazine induced myopericarditis in a patient with ulcerative colitis.
(2017-11)A 25-year-old male with a background of ulcerative colitis presented with a two-week history of central chest pain. His ECG on presentation showed global T wave inversion with a peak troponin I of 165 ng/ml. Clinical ... -
Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma.
(2020-09)INTRODUCTION: Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. As the median survival for patients with mesothelioma is 12.1 ... -
A meta-analysis of remote ischaemic conditioning in experimental stroke.
(2020-06)Remote ischaemic conditioning (RIC) is achieved by repeated transient ischaemia of a distant organ/limb and is neuroprotective in experimental ischaemic stroke. However, the optimal time and methods of administration are ... -
Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome.
(2020-05)Background: The Central Indian gut microbiome remains grossly understudied. Herein, we sought to investigate the burden of antimicrobial resistance and diarrheal diseases, particularly Clostridioides difficile , in ... -
Metallosis in a total knee arthroplasty
(2014-03)A 70-year-old woman presented with right knee pain and a ‘grinding’ sensation 6 months after a total knee replacement for osteoarthritis. Clinical examination revealed a valgus deformity, patellofemoral crepitus and a ... -
A Method to Evaluate Trainee Progression During Simulation Training at the Urology Simulation Boot Camp (USBC) Course.
(2018-08)OBJECTIVES: To evaluate skills progression at the Urology Simulation Boot Camp (USBC), a course intended to provide urology trainees with 32 hours of 1:1 training on low and high-fidelity simulators. DESIGN: In this ... -
Microfracture Technique for Chronic Unstable Osteochondral Defect of Knee: Case Report
(2021-02)Osteochondral fractures of the medial femoral condyle of the knee can be diagnostically and therapeutically challenging. Various techniques of osteochondral defect treatment include fixation, abrasion chondroplasty, drilling, ... -
MicroRNAs: relevant tools for a colorectal surgeon?
(2012-04)Colorectal cancer is the third most common malignancy and cause of cancer-related deaths worldwide. Approximately half of the patients diagnosed with colorectal cancer ultimately die of the condition. Death from colorectal ... -
Mid term functional results following surgical treatment of recto-urinary fistulas postprostate cancer treatment.
(2018-09)INTRODUCTION: To evaluate the mid term functional results of patients treated for RUF and to determine an optimal treatment strategy to improve their quality of life. Recto-urinary Fistula (RUF) is a rare complication ... -
Mid-bundle positioning of the femoral socket increases graft rupture in anatomic single bundle anterior cruciate ligament reconstruction.
(2018-09)BACKGROUND: Anatomic anterior cruciate ligament (ACL) reconstructions are superior to non-anatomic graft placements with regard to controlling rotational laxity. Different techniques of anatomic single-bundle reconstruction ... -
Mid-long term survivorship of the cemented, semi-constrained "Discovery" total elbow arthroplasty
(2021-01)Background: The incidence of total elbow arthroplasty (TEA) is increasing and improved understanding of elbow kinematics and biomaterials have driven advances in implant design. In modern practice, cemented semi-constrained ... -
Mid-Term Remission of Type 2 Diabetes Mellitus After Laparoscopic Roux En-Y Gastric Bypass
(2016-06)BACKGROUND: Laparoscopic Roux en-Y gastric bypass (LRYGB) is an established therapeutic modality for type 2 diabetes mellitus (T2DM). However, there is paucity of data on the outcomes of LRYGB on T2DM beyond 2 years. This ... -
Midterm results with Birmingham Hip Resurfacing/Synergy stem modular metal-on-metal total hip arthroplasty.
(2013-08)Large head modular metal-on-metal total hip replacement (MoMTHR) has been shown to have increased revision rates in the National joint registry and in literature. We reviewed 41 consecutive patients with 44 hips who had ... -
Mini-clinical evaluation exercise in anaesthesia training
(2009)BACKGROUND: The Mini-Clinical Evaluation Exercise (Mini-CEX) is a workplace-based assessment tool of potential value in anaesthesia to assess and improve clinical performance. Its reliability and positive educational impact ... -
Minimally Invasive Circumferential Hiatal Dissection for the Treatment of Adenocarcinoma of the Distal Esophagus and Esophago-gastric Junction: Technical Considerations Combined With Histopathological Outcomes.
(2019-06)BACKGROUND/AIM: Circumferential resection margin involvement is an independent prognostic factor in patients with adenocarcinoma of the distal esophagus and esophago-gastric junction. However, there is currently no consensus ... -
MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium.
(2017-03)Leukocyte adhesion to brain endothelial cells, the blood-brain barrier main component, is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Leukocyte adhesion is mediated ...
