Browsing by Title
Now showing items 1557-1576 of 1801
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The Association between Polyclonal Combined Serum Free Light Chain Concentration and Mortality in Individuals with Early Chronic Kidney Disease.
(2015-07)A major component of increased mortality risk in people with chronic kidney disease (CKD) is associated with non-traditional cardiovascular risk factors including markers of inflammation. We studied whether a novel marker ... -
The audacity of hope: tyranny or liberation in dementia care
(2014)The introduction of cognitive enhancing medication has created an expectation that drug treatment is a significant part of dementia management to the point that rate of cholinesterase inhibitor prescribing has been suggested ... -
The benefit of radiologically-guided steroid injections for trapeziometacarpal osteoarthritis.
(2010-11)INTRODUCTION: Osteoarthritis of the trapeziometacarpal joint (TMJ) is a common condition causing significant disability. Conservative treatments include intra-articular steroid injections. PATIENTS AND METHODS: This clinical, ... -
The bowel cancer awareness campaign 'Be Clear on Cancer': sustained increased pressure on resources and over-accessed by higher social grades with no increase in cancer detected.
(2016-02)AIM: To evaluate the impact of the national 'Be Clear on Cancer' bowel cancer reminder campaign on service and diagnosis at a single UK institution. Secondly, to evaluate the socio-economic background of patients referred ... -
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The burden of comorbidity in people with chronic kidney disease stage 3: a cohort study.
(2015-12)BACKGROUND: Multimorbidity is a growing concern for healthcare systems, with many countries experiencing demographic transition to older population profiles. Chronic kidney disease (CKD) is common but often considered in ... -
The clinical utility and cost impact of cystatin C measurement in the diagnosis and management of chronic kidney disease: A primary care cohort study.
(2017-10)BACKGROUND: To reduce over-diagnosis of chronic kidney disease (CKD) resulting from the inaccuracy of creatinine-based estimates of glomerular filtration rate (GFR), UK and international guidelines recommend that ... -
The cost of ignoring acute cholecystectomy
(2009)INTRODUCTION: Biliary symptoms whilst awaiting elective cholecystectomy are common, resulting in hospital admission, further investigation and increased hospital costs. Immediate cholecystectomy during the first admission ... -
The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
(2017-07)BACKGROUND: To assess the within-trial cost-effectiveness of an NHS ovarian cancer screening (OCS) programme using data from UKCTOCS and extrapolate results based on average life expectancy. METHODS: Within-trial economic ... -
The design of compassionate care.
(2014)Aims and objectives. To investigate the tension between individual and organisational responses to contemporary demands for compassionate interactions in health care. Background. Health care is often said to need more ... -
The development and initial validation of a questionnaire to measure help-seeking behaviour in patients with new onset rheumatoid arthritis.
(2015-12)BACKGROUND: Early treatment for rheumatoid arthritis (RA) is vital. However, people often delay in seeking help at symptom onset. An assessment of the reasons behind patient delay is necessary to develop interventions to ... -
The diagnostic accuracy of spectral-domain optical coherence tomography for neovascular age-related macular degeneration: a comparison with fundus fluorescein angiography.
(2015-05)PURPOSE: To evaluate the diagnostic accuracy of spectral-domain optical coherence tomography (SD-OCT) for neovascular age-related macular degeneration (nAMD): a comparison against fundus fluorescein angiography (FFA). ... -
The dietary management of patients with diabetes and renal disease: challenges and practicalities.
(2012-02)Diabetes mellitus is one of the major causes of chronic kidney disease and end-stage renal disease. Diet and lifestyle modification are vital components of optimal treatment for both conditions. This paper will address ... -
The effect of anaesthetist grade and frequency of insertion on epidural failure: a service evaluation in a United Kingdom teaching hospital.
(2015-01)BACKGROUND: Despite being a commonly performed procedure, epidural catheter insertion has a significant failure rate. There is a lack of guidance as to how regularly the procedure should be performed in order to maintain ... -
The effect of influenza vaccination on the incidence of chronic obstructive pulmonary disease exacerbations in the immediate postvaccination period
(2009)BACKGROUND: Influenza vaccination is an important strategy in the prevention of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Despite the proven benefits, there are patients who are reluctant ... -
The effectiveness and cost of corticosteroid injection and physiotherapy in the treatment of frozen shoulder-a single-centre service evaluation.
(2014-07)Frozen shoulder is a common condition resulting in pain, stiffness and functional impairment. Symptoms can persist for months or even years if left untreated. Various treatments are available, but a standard care package ...
