β-Adrenoreceptor agonists in the management of pain associated with renal colic: A systematic review.
|dc.identifier.citation||BMJ Open. 2016 Jun 20;6(6):e011315. doi: 10.1136/bmjopen-2016-011315.||language|
|dc.description.abstract||OBJECTIVES: To determine whether β-adrenoreceptor agonists are effective analgesics for patients with renal colic through a systematic review of the literature. SETTING: Adult emergency departments or acute assessment units. PARTICIPANTS: Human participants with proven or suspected renal colic. INTERVENTIONS: β-adrenoreceptor agonists. OUTCOME MEASURES: Primary: level of pain at 30 min following administration of the β-agonist. Secondary: level of pain at various time points following β-agonist administration; length of hospital stay; analgesic requirement; stone presence, size and position; degree of hydronephrosis. RESULTS: 256 records were screened and 4 identified for full-text review. No articles met the inclusion criteria. CONCLUSIONS AND IMPLICATIONS: There is no evidence to support or refute the proposed use of β-agonists for analgesia in patients with renal colic. Given the biological plausibility and existing literature base, clinical trials investigating the use of β-adrenoreceptor agonists in the acute setting for treatment of the pain associated with renal colic are recommended. TRIAL REGISTRATION NUMBER: CRD42015016266.||language|
|dc.title||β-Adrenoreceptor agonists in the management of pain associated with renal colic: A systematic review.||language|
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