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dc.contributor.authorTabner, Andrew
dc.contributor.authorJohnson, Graham
dc.contributor.authorFakis, Apostolos
dc.contributor.authorSurtees, Jane
dc.contributor.authorLennon, Robert
dc.date.accessioned2016-08-17T09:03:47Z
dc.date.available2016-08-17T09:03:47Z
dc.date.issued2016-06
dc.identifier.citationBMJ Open. 2016 Jun 20;6(6):e011315. doi: 10.1136/bmjopen-2016-011315.language
dc.identifier.urihttps://orda.derbyhospitals.nhs.uk/handle/123456789/100
dc.description.abstractOBJECTIVES: To determine whether β-adrenoreceptor agonists are effective analgesics for patients with renal colic through a systematic review of the literature. SETTING: Adult emergency departments or acute assessment units. PARTICIPANTS: Human participants with proven or suspected renal colic. INTERVENTIONS: β-adrenoreceptor agonists. OUTCOME MEASURES: Primary: level of pain at 30 min following administration of the β-agonist. Secondary: level of pain at various time points following β-agonist administration; length of hospital stay; analgesic requirement; stone presence, size and position; degree of hydronephrosis. RESULTS: 256 records were screened and 4 identified for full-text review. No articles met the inclusion criteria. CONCLUSIONS AND IMPLICATIONS: There is no evidence to support or refute the proposed use of β-agonists for analgesia in patients with renal colic. Given the biological plausibility and existing literature base, clinical trials investigating the use of β-adrenoreceptor agonists in the acute setting for treatment of the pain associated with renal colic are recommended. TRIAL REGISTRATION NUMBER: CRD42015016266.language
dc.language.isoenlanguage
dc.subjectRenal Coliclanguage
dc.subjectlanguage
dc.titleβ-Adrenoreceptor agonists in the management of pain associated with renal colic: A systematic review.language
dc.typeArticlelanguage


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