Browsing Gynaecology by Title
Now showing items 1-20 of 49
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Acute herpes simplex encephalitis in pregnancy.
(2015-03) -
An audit of outpatient hysteroscopy in Royal Derby Hospital
(2014-04)Introduction Hysteroscopy offers an extension of the gynaecologists' armamentarium as it improves the diagnostic accuracy and permits better treatment of abnormal intra-uterine conditions. All gynaecological units should ... -
Assessment of Circulating Anti-Müllerian Hormone in Women Using Hormonal Contraception: A Systematic Review.
(2019-07)Background: The status of ovarian reserve markers during hormonal contraception (HC) remains uncertain with conflicting literature data. The purpose of this study was to assess the impact of HC on circulating anti-Müllerian ... -
A case of caesarean scar ectopic pregnancy-successful treatment with intra-amniotic methotrexate followed by a systemic course of intramuscular methotrexate
(2013-12)Case: A 34-year-old woman, G5 P2 was seen at the Royal Derby Hospital in early pregnancy. Previous deliveries were by emergency caesarean section, the first at 30 weeks of gestation for a ruptured uterus and the second at ... -
Case report of eclampsia complicated with spontaneous splenic rupture
(2018-04)Objectives We present a case report of eclampsia complicated with spontaneous rupture of spleen. Design A case report and literature search. Setting Queens hospital Burton on Trent. A 33 year old primigravida under low ... -
Chemotherapy improves survival rate in Stage 1 ovarian cancers
(2018)Purpose of Investigation: The role of adjuvant chemotherapy in Stage 1 ovarian cancer is conflicting with no clear evidence to support adjuvant chemotherapy versus observation alone. The authors sought to establish the ... -
Comparing the experience of enhanced recovery programme for gynaecological patients undergoing laparoscopic versus open gynaecological surgery: a prospective study.
(2018-06)Background: Enhanced recovery has been shown to improve patients' experience after surgery. There are no previous studies comparing patients' experience between those undergoing laparoscopic and open gynaecological surgery. ... -
Complete cytoreduction after five or more cycles of neo-adjuvant chemotherapy confers a survival benefit in advanced ovarian cancer.
(2018-01)OBJECTIVES: To assess the impact of 5 or more cycles of neoadjuvant chemotherapy (NACT) and cytoreductive outcomes on overall survival (OS) in patients undergoing interval debulking surgery (IDS) for advanced ovarian ... -
Diaphragm disease in advanced ovarian cancer: Predictability of pre-operative imaging and safety of surgical intervention.
(2018-05)OBJECTIVES: To establish the positive predictive values of pre-operative identification with CT imaging of metastatic diaphragm disease in surgically managed cases of advanced ovarian cancer (AOC). Additionally, we have ... -
Does sites of recurrence impact survival in secondary cytoreduction surgery for recurrent epithelial ovarian cancer?
(2020-01)Outcomes of secondary cytoreduction surgery (SCS) were evaluated for morbidity, progression free survival (PFS) and overall survival (OS) and factors influencing results were explored. Retrospective analysis of all cases ... -
Double-blind randomized controlled trial of letrozole versus clomiphene citrate in subfertile women with polycystic ovarian syndrome
(2017-06)STUDY QUESTION: Would letrozole as a primary ovulation induction agent generate better pregnancy rates than clomiphene citrate (CC) in subfertile women with anovulatory polycystic ovarian syndrome (PCOS)? SUMMARY ANSWER: ... -
Eag and HERG potassium channels as novel therapeutic targets in cancer.
(2010-12)Voltage gated potassium channels have been extensively studied in relation to cancer. In this review, we will focus on the role of two potassium channels, Ether à-go-go (Eag), Human ether à-go-go related gene (HERG), in ... -
Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells
(2017)Background: Antipsychotics (APs) are widely prescribed drugs, which are well known to cause reproductive adverse effects through mechanisms yet to be determined. The purpose of this study was to investigate the effect of ... -
Effect of transfer of a poor quality embryo along with a top quality embryo on the outcome during fresh and frozen in vitro fertilization cycles.
(2018-09)OBJECTIVE: To evaluate the impact of a poor quality embryo (PQE) during double ET (DET) with a top quality embryo (TQE) on IVF outcome. DESIGN: A review of prospectively collected data. SETTING: Tertiary level fertility ... -
Effect of transfer of a poor quality embryo along with a top quality embryo on the outcome during fresh and frozen in vitro fertilization cycles.
(2018-09)OBJECTIVE: To evaluate the impact of a poor quality embryo (PQE) during double E (DET) with a top quality embryo (TQE) on IVF outcome. DESIGN: A review of prospectively collected data. SETTING: Tertiary level fertility ... -
Enigma of urethral pain syndrome: why are there so many ascribed etiologies and therapeutic approaches?
(2014-06)Urethral pain syndrome has had several sobriquets, which have led to much confusion over the existence of this pathological condition and the useful options in the care of the afflicted patient. Our aim was to explore the ... -
Experiences of enhanced recovery after surgery in general gynaecology patients:An interpretative phenomenological analysis.
(2019-07)There is little qualitative research exploring non-cancer gynaecology patients' experiences of enhanced recovery after surgery (ERAS) protocols. Seven women participated in audio-recorded interviews, discussing their ... -
Female adipocyte androgen synthesis and the effects of insulin
(2014-06)The metabolic syndrome is a cluster of metabolic disorders characterized by insulin resistance and hyperinsulinaemia, and its presence can increase the risk of cardiovascular disease significantly. The metabolic syndrome ... -
Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary
(2017)OBJECTIVE: The pathogenesis of polycystic ovary syndrome (PCOS), a common endocrine disease and metabolic disturbance, is still unknown. The aim of the study was to investigate whether patients with PCOS display increased ...
