Browsing Medicine Division by Issue Date
Now showing items 1-20 of 110
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Pain sensitivity in healthy volunteers and people with knee Osteoarthritis
(2012)Background: Osteoarthritis (OA) is the most common form of arthritis worldwide and a major cause of pain and disability, and yet underlying mechanisms of OA pain are not entirely understood. There is compelling evidence ... -
Quantitative sensory testing in painful osteoarthritis: a systematic review and meta-analysis.
(2012-10-20)Summary: Objective: To systematically review the use of Quantitative sensory testing (QST) in pain characterisation (phenotyping) in Osteoarthritis (OA). Methods: Six bibliographic databases (Medline, Embase, Amed, Cinahl, ... -
Investigating pleural thickening.
(2013-01)Downer, N, Ali, N, & Au-Yong, I 2013, 'Investigating pleural thickening', BMJ: British Medical Journal, 346, 7890, pp. 35-37. -
Exenatide improves excessive daytime sleepiness and wakefulness in obese patients with type 2 diabetes without obstructive sleep apnoea.
(2013-02)We investigate the effects of exenatide on excessive daytime sleepiness (EDS), driving performance and depression score in patients with type 2 diabetes with EDS. Eight obese patients with diabetes but without obstructive ... -
Vitamin D and skeletal muscle strength and endurance in COPD.
(2013-02)Jackson, A, Shrikrishna, D, Kelly, J, Kemp, S, Hart, N, Moxham, J, Polkey, M, Kemp, P, & Hopkinson, N 2013, 'Vitamin D and skeletal muscle strength and endurance in COPD', The European Respiratory Journal, 41, 2, pp. 309-316. -
The Impact of a Decision Support Tool Linked to an Electronic Medical Record on Glycemic Control in People with Type 2 Diabetes.
(2013-05)Aims: We retrospectively compared glycemic control and glycemic burden in type 2 diabetes patients treated by general physicians with access to decision support with those treated by general physicians without access to ... -
Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles.
(2013-05)Summary Background Dose intensification with a combination of cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) every 2 weeks improves outcomes in patients older than 60 years with diffuse large B-cell ... -
Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort
(2013-05)BACKGROUND: Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline ... -
Bronchoscopic intrabullous autologous blood instillation: a novel approach for the treatment of giant bullae.
(2013-10)The current standard therapy for patients with giant bullae is surgical bullectomy; however, high operative risk and comorbidities preclude surgical procedures in many patients. Autologous blood instilled directly into ... -
Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized phase II study
(2013-12)BACKGROUND: A reduced exercise capacity is associated with increased morbidity and mortality in patients with advanced non-small cell lung cancer (NSCLC). Therapeutic exercise can be beneficial and neuromuscular electrical ... -
Work disability and state benefit claims in early rheumatoid arthritis: the ERAN cohort.
(2014-03)Objective: RA is an important cause of work disability. This study aimed to identify predictive factors for work disability and state benefit claims in a cohort with early RA. Methods: The Early RA Network (ERAN) inception ... -
Structural associations of symptomatic knee osteoarthritis.
(2014-11)Objective: Structural changes of osteoarthritis (OA) may occur in the absence of pain. In this study, we aimed to identify histopathologic features that are associated with symptomatic knee OA. Methods: Medial tibial ... -
Acute Transient Stress Induced Adrenal Hypertrophy and Adrenal Medullary Hyperactivity.
(2015)Objectives: Adrenal gland hypertrophy can be related to acute stress with abnormal adrenal function tests. It may not always need treatment. Material and methods: An acute presentation of adrenal gland hypertrophy following ... -
A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis.
(2015-01-20)INTRODUCTION: Pain remains the most important problem for people with rheumatoid arthritis (RA). Active inflammatory disease contributes to pain, but pain due to non-inflammatory mechanisms can confound the assessment ... -
Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial.
(2015-02-14)Background: High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether to continue or temporarily withdraw existing antihypertensive drugs, ... -
Endobronchial Coils for Severe Emphysema Are Effective Up to 12 Months following Treatment: Medium Term and Cross-Over Results from a Randomised Controlled Trial.
(2015-04)BACKGROUND: There is a clinical need for therapeutic options to reduce hyperinflation associated with severe emphysema. Endobronchial Coils (coils) are nitinol devices implanted bronchoscopically under fluoroscopic guidance ... -
Energy and nutrient intakes of Sri Lankan patients with type 2 diabetes mellitus: a cross-sectional survey.
(2015-08-12)Background: Sri Lanka has a high prevalence of type 2 diabetes mellitus. Energy and macronutrient intakes of diabetic patients have not been previously studied in this population. We aimed to clarify the energy and nutrient ... -
The Clots in Legs Or sTockings after Stroke (CLOTS) 3 trial: a randomised controlled trial to determine whether or not intermittent pneumatic compression reduces the risk of post-stroke deep vein thrombosis and to estimate its cost-effectiveness.
(2015-09)Background: Venous thromboembolism (VTE) is a common cause of death and morbidity in stroke patients. There are few data concerning the effectiveness of intermittent pneumatic compression (IPC) in treating patients with ...
