Diabetes & Endocrinology
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Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans.
(2020-01-16)Objective: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated ... -
Pharmacotherapy of type 2 diabetes mellitus in frail elderly patients.
(2019-12)The prevalence of type 2 diabetes mellitus is expected to rise in the frail elderly population, which will have significant consequences for the health economy. Symptoms of hypoglycaemia can be subtle in the elderly. ... -
Acidophil stem cell pituitary adenoma: a case report and literature review.
(2019-12)In this article, we describe a very rare case of pituitary acidophilic stem cell adenoma, accompanied by a literature review. We present the case of 33-year-old woman with a history of amenorrhea, galactorrhea, elevated ... -
Acute Transient Stress Induced Adrenal Hypertrophy and Adrenal Medullary Hyperactivity.
(2015)Objectives: Adrenal gland hypertrophy can be related to acute stress with abnormal adrenal function tests. It may not always need treatment. Material and methods: An acute presentation of adrenal gland hypertrophy following ... -
Energy and nutrient intakes of Sri Lankan patients with type 2 diabetes mellitus: a cross-sectional survey.
(2015-08-12)Background: Sri Lanka has a high prevalence of type 2 diabetes mellitus. Energy and macronutrient intakes of diabetic patients have not been previously studied in this population. We aimed to clarify the energy and nutrient ... -
Hypoglyceamia in a patient with a solitary fibrous tumour.
(2016-04)Objective: To illustrate an unusual mechanism causing hypoglycaemia. Material and methods: A 76-year-old man presented with episodes of agitation and confusion and was resuscitated with oral glucose gel when found to be ... -
Rising HbA1c in the presence of optimal glycaemic control as assessed by self-monitoring - iron deficiency anaemia.
(2016-02)HbA1c can be affected by determinants other than glucose and an awareness of this is important to avoid unnecessary hypoglycaemia. -
Association of FTO and near MC4R variants with obesity measures in urban and rural dwelling Sri Lankans
(2016-09)Objectives: To investigate the association between the fat mass and obesity related (FTO) gene rs9939609 and near melanocortin-4-receptor (MC4R) gene rs17782313 polymorphisms with obesity measures and metabolic parameters ... -
Dysautonomia: An explanation for the medically unexplained?
(2016)Objective: To identify dysautonomia as a collection of conditions with variable presentation that may be mistaken for medically unexplained symptoms. Methods: Case series. Results: Tilt table testing and 24 h electrocardiographic ... -
The Impact of a Decision Support Tool Linked to an Electronic Medical Record on Glycemic Control in People with Type 2 Diabetes.
(2013-05)Aims: We retrospectively compared glycemic control and glycemic burden in type 2 diabetes patients treated by general physicians with access to decision support with those treated by general physicians without access to ... -
Exenatide improves excessive daytime sleepiness and wakefulness in obese patients with type 2 diabetes without obstructive sleep apnoea.
(2013-02)We investigate the effects of exenatide on excessive daytime sleepiness (EDS), driving performance and depression score in patients with type 2 diabetes with EDS. Eight obese patients with diabetes but without obstructive ... -
A prospective longitudinal study of Pasireotide in Nelson's syndrome.
(2018-01)PURPOSE: Nelson's syndrome is a challenging condition that can develop following bilateral adrenalectomy for Cushing's disease, with high circulating ACTH levels, pigmentation and an invasive pituitary tumor. There is no ...
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