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dc.contributor.authorTOPKAT
dc.contributor.authorSherwood Forest Hospitals NHS Foundation Trust
dc.date.accessioned2020-07-28T16:04:41Z
dc.date.available2020-07-28T16:04:41Z
dc.date.issued2020-04
dc.identifier.citationBeard, D. J. et al. (2020) ‘Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT’, Health technology assessment (Winchester, England), 24(20), pp. 1–98. doi: 10.3310/hta24200.en
dc.identifier.otherISRCTN/ISRCTN03013488
dc.identifier.otherPMCID: PMC7232134
dc.identifier.otherDOI: 10.3310/hta24200
dc.identifier.urihttps://orda.derbyhospitals.nhs.uk/handle/123456789/2286
dc.descriptionAll NIHR Journals Library reports have been produced under the terms of a commissioning contract issued by the Secretary of State for Health. Reports may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising.en
dc.description.abstractBackground: Late-stage medial compartment knee osteoarthritis can be treated using total knee replacement or partial (unicompartmental) knee replacement. There is high variation in treatment choice and insufficient evidence to guide selection. Objective: To assess the clinical effectiveness and cost-effectiveness of partial knee replacement compared with total knee replacement in patients with medial compartment knee osteoarthritis. The findings are intended to guide surgical decision-making for patients, surgeons and health-care providers. Design: This was a randomised, multicentre, pragmatic comparative effectiveness trial that included an expertise component. The target sample size was 500 patients. A web-based randomisation system was used to allocate treatments.en
dc.description.sponsorshipThis project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme.en
dc.language.isoenen
dc.subjectKnee Replacementen
dc.subjectArthroplastyen
dc.subjectKnee Osteoarthritis
dc.titleTotal versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCTen
dc.typeTechnical Reporten


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