Browsing Dementia by Author "Thacker, Simon"
Now showing items 1-7 of 7
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Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: Study protocol for a randomised controlled trial (ELAD study)
Thacker, Simon (2019)Background: Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue currently approved for type 2 diabetes and obesity. Preclinical evidence in transgenic models of Alzheimer's disease suggests that liraglutide exerts ... -
Peripheral insulin resistance does not correlate with cerebral glucose metabolic rate in non-diabetic alzheimer's patients
Thacker, Simon (2018)Background: Type 2 diabetes is a risk factor for Alzheimer disease (AD) and several studies have shown that insulin signalling is impaired in AD brain. Progressive brain hypometabolism is a hallmark of AD and can be evaluated ... -
Psychiatry and the geriatric syndromes: Creating constructive interfaces
Thacker, Simon; Skelton, Mike (2017)Integrating mental and physical healthcare is difficult to achieve because of professional and organisational barriers. Psychiatrists recognise the problems resulting from fragmentation of services and want continuity of ... -
Screening for dementia in primary care.
Thacker, Simon (2013)The literature on the diagnosis of dementia in primary care has been summarised in a meta-analysis that indicated that GPs recognise three in four patients with dementia using clinical judgment alone whilst highlighting ... -
The audacity of hope: tyranny or liberation in dementia care
Prakash, Anthony; Thacker, Simon (2014)The introduction of cognitive enhancing medication has created an expectation that drug treatment is a significant part of dementia management to the point that rate of cholinesterase inhibitor prescribing has been suggested ... -
Treatments for delusional disorder
Skelton, Mike; Thacker, Simon (2015)Background Delusional disorder is commonly considered to be difficult to treat. Antipsychotic medications are frequently used and there is growing interest in a potential role for psychological therapies such as cognitive ... -
Treatments for delusional disorder.
Skelton, Mike; Thacker, Simon (2015)Background Delusional disorder is commonly considered to be difficult to treat. Antipsychotic medications are frequently used and there is growing interest in a potential role for psychological therapies such as cognitive ...